{"id":242967,"date":"2026-05-10T09:18:00","date_gmt":"2026-05-10T13:18:00","guid":{"rendered":"https:\/\/news-you-need.com\/index.php\/2026\/05\/10\/yale-led-technology-receives-fda-approval-for-breast-cancer-treatment\/"},"modified":"2026-05-10T09:30:07","modified_gmt":"2026-05-10T13:30:07","slug":"yale-led-technology-receives-fda-approval-for-breast-cancer-treatment","status":"publish","type":"post","link":"https:\/\/news-you-need.com\/index.php\/2026\/05\/10\/yale-led-technology-receives-fda-approval-for-breast-cancer-treatment\/","title":{"rendered":"Yale-led Technology Receives FDA Approval For Breast Cancer Treatment"},"content":{"rendered":"

Yale-led Technology Receives FDA Approval For Breast Cancer Treatment<\/a><\/p>\n

https:\/\/goldrushcam.com\/sierrasuntimes\/index.php\/news\/local-news\/77972-yale-led-technology-receives-fda-approval-for-breast-cancer-treatment<\/a><\/p>\n

Publish Date: 2026-05-10 09:18:00<\/a><\/p>\n

Source Domain: goldrushcam.com<\/a><\/p>\n

Image by\u00a0Marco Jean de Oliveira Teixeir Marco Jean de Oliveira Teixeir\u00a0from\u00a0Pixabay<\/span><\/p>\n

The biotech company Arvinas was originally founded based on pioneering research from Yale chemist Craig Crews into\u00a0PROTAC\u00a0protein\u00a0degraders.<\/p>\n

May 10, 2026 – By\u00a0Meg Dalton –\u00a0More than a decade ago, Yale chemist Craig Crews founded a biotechnology company in New Haven based on his \"yale510pioneering research into\u00a0PROTACs (or\u00a0PROteolysis\u00a0TArgeting Chimera), a technology that treats certain types of cancer and other diseases by degrading the proteins that cause\u00a0them.\u00a0<\/p>\n

Craig Crews\u00a0\u00a0Photo by Marissa Fiorucci<\/p>\n

That company, Arvinas, has since developed a\u00a0PROTAC<\/span>\u00a0therapy called vepdegestrant, which is now helping patients living with breast\u00a0cancer.\u00a0<\/p>\n

Last week, vepdegestrant, which is developed by Arvinas and Pfizer under the brand name Veppanu, became the first\u00a0PROTAC<\/span>\u00a0therapy\u00a0to be approved\u00a0by the\u00a0U.S.<\/span>\u00a0Food and Drug\u00a0Administration.\u00a0<\/p>\n

The once-daily oral therapy will be available as treatment for adults with estrogen receptor-positive, human epidermal growth factor receptor 2-negative,\u00a0ESR1<\/span>-mutated advanced or metastatic breast cancer. Breast cancer is the most common cancer among women worldwide, with many tumors driven by estrogen receptor\u00a0signaling.<\/p>\n

For Crews, the\u00a0FDA<\/span>\u00a0approval of vepdegestrant as a treatment for breast cancer now has additional personal\u00a0meaning.\u00a0<\/p>\n

\u201cI\u2019m thrilled that breast cancer patients will have an additional option for treatment,\u201d said Crews<\/strong>, who is the John C. Malone Professor of Molecular, Cellular, and Developmental Biology and professor of chemistry in Yale\u2019s Faculty of Arts and Sciences and professor of pharmacology at Yale School of Medicine. \u201cMy mother was diagnosed last year with breast cancer, and so I know the challenges that patients and their families face with thinking about therapeutic\u00a0options.\u201d\u00a0<\/p>\n

Largely pioneered at Yale,\u00a0PROTAC<\/span>s have already inspired dozens of other companies that are developing degrader…<\/p>\n

Source<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Yale-led Technology Receives FDA Approval For Breast Cancer Treatment https:\/\/goldrushcam.com\/sierrasuntimes\/index.php\/news\/local-news\/77972-yale-led-technology-receives-fda-approval-for-breast-cancer-treatment Publish Date: 2026-05-10 09:18:00 Source…<\/p>\n","protected":false},"author":1,"featured_media":242968,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"fifu_image_url":"https:\/\/goldrushcam.com\/sierrasuntimes\/images\/2026\/may\/breast-cancer-marcojean20-breast-cancer-6701684_640.jpg","fifu_image_alt":"","footnotes":""},"categories":[8],"tags":[],"class_list":["post-242967","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-technology"],"_links":{"self":[{"href":"https:\/\/news-you-need.com\/index.php\/wp-json\/wp\/v2\/posts\/242967"}],"collection":[{"href":"https:\/\/news-you-need.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/news-you-need.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/news-you-need.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/news-you-need.com\/index.php\/wp-json\/wp\/v2\/comments?post=242967"}],"version-history":[{"count":1,"href":"https:\/\/news-you-need.com\/index.php\/wp-json\/wp\/v2\/posts\/242967\/revisions"}],"predecessor-version":[{"id":242969,"href":"https:\/\/news-you-need.com\/index.php\/wp-json\/wp\/v2\/posts\/242967\/revisions\/242969"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/news-you-need.com\/index.php\/wp-json\/wp\/v2\/media\/242968"}],"wp:attachment":[{"href":"https:\/\/news-you-need.com\/index.php\/wp-json\/wp\/v2\/media?parent=242967"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/news-you-need.com\/index.php\/wp-json\/wp\/v2\/categories?post=242967"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/news-you-need.com\/index.php\/wp-json\/wp\/v2\/tags?post=242967"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}