{"id":232772,"date":"2026-04-09T04:51:00","date_gmt":"2026-04-09T08:51:00","guid":{"rendered":"https:\/\/news-you-need.com\/index.php\/2026\/04\/09\/single-cell-method-to-improve-immunotherapy\/"},"modified":"2026-04-09T05:05:12","modified_gmt":"2026-04-09T09:05:12","slug":"single-cell-method-to-improve-immunotherapy","status":"publish","type":"post","link":"https:\/\/news-you-need.com\/index.php\/2026\/04\/09\/single-cell-method-to-improve-immunotherapy\/","title":{"rendered":"Single-Cell Method To Improve Immunotherapy"},"content":{"rendered":"<p><a href=\"https:\/\/www.technologynetworks.com\/tn\/news\/rna-alone-doesnt-tell-the-full-immune-story-411467\">Single-Cell Method To Improve Immunotherapy<\/a><\/p>\n<p><a href=\"https:\/\/www.technologynetworks.com\/tn\/news\/rna-alone-doesnt-tell-the-full-immune-story-411467\">https:\/\/www.technologynetworks.com\/tn\/news\/rna-alone-doesnt-tell-the-full-immune-story-411467<\/a><\/p>\n<p>Publish Date: <a href=\"publish_date]\">2026-04-09 04:51:00<\/a><\/p>\n<p>Source Domain: <a href=\"www.technologynetworks.com\">www.technologynetworks.com<\/a><\/p>\n<p class=\"stk-block-text__text has-text-align-left\">Our immune system is constantly making decisions. Immune cells sense danger, send signals, call for backup and sometimes attack. Scientists have long studied these decisions by reading RNA. But RNA doesn\u2019t always tell the full story.<\/p>\n<p class=\"stk-block-text__text has-text-align-left\">At\u00a0Sylvester Comprehensive Cancer Center,\u00a0part of the University of Miami Miller School of Medicine, researchers have developed a way to see what immune cells are actually doing, not just what they intend to do. A new technology called CIPHER-seq lets scientists simultaneously measure both RNA and proteins within the same individual immune cell, offering a clearer picture of how immune responses work.<\/p>\n<p class=\"stk-block-text__text has-text-align-left\">The study was led by a multidisciplinary team based at Sylvester and the Miller School, with collaborators from the University of California, San Francisco, and the Helen Diller Family Comprehensive Cancer Center. The work brings together expertise in cancer biology, hematology, immunology, genomics, flow cytometry and molecular biology and\u00a0is detailed in\u00a0Scientific Reports.<\/p>\n<p class=\"stk-block-text__text has-text-align-left\">\u201cRNA gives us clues about where a cell is headed,\u201d said\u00a0Justin Taylor, M.D.,\u00a0Sylvester researcher, co-senior author of the study and associate professor of\u00a0hematology\u00a0at the Miller School. \u201cProteins show us where it actually arrives, and this clearer picture could help scientists design better immunotherapies and help clinicians predict which patients are most likely to benefit from them.\u201d<\/p>\n<p><h2 class=\"stk-block-heading__text has-text-align-left\">Why RNA Alone Can Be Misleading<\/h2>\n<\/p>\n<p class=\"stk-block-text__text has-text-align-left\">Single\u2011cell RNA sequencing has transformed biomedical research. It allows scientists to study thousands of immune cells at once and see which genes are turned on or off. But RNA is only a set of instructions. Proteins are the molecules that carry out those instructions.<\/p>\n<p class=\"stk-block-text__text has-text-align-left\">That gap becomes especially important when scientists study cytokines. These small but powerful proteins that immune cells use to communicate help control inflammation, direct immune attacks and shape how tumors grow or shrink. Yet RNA levels for cytokines&#8230;<\/p>\n<p><a href=\"https:\/\/www.technologynetworks.com\/tn\/news\/rna-alone-doesnt-tell-the-full-immune-story-411467\">Source<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Single-Cell Method To Improve Immunotherapy https:\/\/www.technologynetworks.com\/tn\/news\/rna-alone-doesnt-tell-the-full-immune-story-411467 Publish Date: 2026-04-09 04:51:00 Source Domain: www.technologynetworks.com Our immune&#8230;<\/p>\n","protected":false},"author":1,"featured_media":232773,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"fifu_image_url":"https:\/\/assets.technologynetworks.com\/production\/dynamic\/images\/content\/411467\/green-fibers-microtubule-unsplash-640x360.jpg?cb=20260409","fifu_image_alt":"","footnotes":""},"categories":[8],"tags":[],"class_list":["post-232772","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-technology"],"_links":{"self":[{"href":"https:\/\/news-you-need.com\/index.php\/wp-json\/wp\/v2\/posts\/232772"}],"collection":[{"href":"https:\/\/news-you-need.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/news-you-need.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/news-you-need.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/news-you-need.com\/index.php\/wp-json\/wp\/v2\/comments?post=232772"}],"version-history":[{"count":1,"href":"https:\/\/news-you-need.com\/index.php\/wp-json\/wp\/v2\/posts\/232772\/revisions"}],"predecessor-version":[{"id":232774,"href":"https:\/\/news-you-need.com\/index.php\/wp-json\/wp\/v2\/posts\/232772\/revisions\/232774"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/news-you-need.com\/index.php\/wp-json\/wp\/v2\/media\/232773"}],"wp:attachment":[{"href":"https:\/\/news-you-need.com\/index.php\/wp-json\/wp\/v2\/media?parent=232772"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/news-you-need.com\/index.php\/wp-json\/wp\/v2\/categories?post=232772"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/news-you-need.com\/index.php\/wp-json\/wp\/v2\/tags?post=232772"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}