Waters Launches 1 mm I.D. Microflow LC Columns with MaxPeak Premier Technology
Waters Launches 1 mm I.D. Microflow LC Columns with MaxPeak Premier Technology
Publish Date: 2026-02-18 09:26:00
Source Domain: www.labmanager.com
Waters Corporation has introduced next-generation 1 mm I.D. liquid chromatography (LC) columns featuring MaxPeak™ Premier Technology across its ACQUITY™, BioResolve™, and GTxResolve™ brands. Designed for high-throughput pharmaceutical and biopharmaceutical laboratories, the new microflow columns are engineered to improve sensitivity while reducing both sample and solvent consumption.
According to the company, the columns deliver up to 2× higher sensitivity than stainless steel microflow columns, helping lower detection and quantitation limits across bioseparations, DMPK, and omics applications. At the same time, they use up to 75% less sample and up to 4× less solvent compared to traditional 2.1 mm I.D. columns.
Higher Sensitivity with Lower Sample and Solvent Consumption
For lab managers balancing performance, sustainability, and cost control, the new microflow format offers measurable advantages. By transitioning from 2.1 mm I.D. analytical-scale LC columns to 1 mm I.D. microflow columns, laboratories can achieve equivalent or improved sensitivity while using only one-quarter of the solvent and sample required for analytical flow.
Key benefits include:
- Up to 2× higher sensitivity than stainless steel microflow columns
- Up to 75% less sample usage compared to 2.1 mm I.D. columns
- Up to 4× reduction in solvent consumption
- Sharper peaks and enhanced peak capacity at low flow rates
- Reduced peak tailing and highly reproducible performance from the first injection
These efficiencies can help laboratories conserve precious materials—particularly in cell and gene therapy and personalized medicine research—while also supporting sustainability initiatives and reducing operating costs.
MaxPeak HPS Technology Improves Recovery and Reproducibility
The 1 mm I.D. columns apply Waters’ MaxPeak High Performance Surface (HPS) Technology to a microflow format. This surface technology minimizes nonspecific adsorption (NSA) and improves analyte recovery for small molecules,…
